All the major inter-theoretic relations of fundamental science are asymptotic ones, e.g. quantum theory as Planck's constant h 0, yielding (roughly) Newtonian mechanics. Thus asymptotics ultimately grounds claims about inter-theoretic explanation, reduction and emergence. This paper examines four recent, central claims by Batterman concerning asymptotics and reduction. While these claims are criticised, the discussion is used to develop an enriched, dynamically-based account of reduction and emergence, to show its capacity to illuminate the complex variety of inter-theory relationships in physics, and (...) to provide a principled resolution to such persistent philosophical problems as multiple realisability and the nature of the special sciences. Introduction Exposition Examination I: Claims (1) and (2), asymptotic explanation and reference Examination II: Claim (3), reduction and singular asymptotics Examination III: Claim (4), emergence and multiple realisability Conclusion. (shrink)

It is shown how the development of physics has involved making explicit what were homocentric projections which had heretofore been implicit, indeed inexpressible in theory. This is shown to support a particular notion of the invariant as the real. On this basis the divergence in ideals of physical intelligibility between Bohr and Einstein is set out. This in turn leads to divergent, but explicit, conceptions of objectivity and completeness for physical theory. *I am indebted to Dr. G. McLelland. Professor F. (...) Rohrlich and an anonymous referee of this journal for several improvements in the formulation of the paper. (shrink)

Contrary to the Empiricist model of science, successful sufficiently fundamental theories not only fit and unify their data fields but also prescribe the general terms in which relevantly to describe observation; specify what is and is not observable; specify the conditions under which what is observable, is observable; specify the instrumental means and reliability by which what is measurable is measured; specify what is causally, statistically, and merely accidentally connected. Moreover, such theories typically require all or most of the entire (...) remainder of science to be properly applied in any given situation and theoreticians' models play a crucial role in such applications. (I call these respectively the internal and external globalnesses of theories.) A discussion of the consequences of these global features of theories for philosophy of science is offered in the context of specific examples and a structural model for science. (shrink)

In his bookMinimal Rationality (1986), Christopher Cherniak draws deep and widespread conclusions from our finitude, and not only for philosophy but also for a wide range of science as well. Cherniak's basic idea is that traditional philosophical theories of rationality represent idealisations that are inaccessible to finite rational agents. It is the purpose of this paper to apply a theory of idealisation in science to Cherniak's arguments. The heart of the theory is a distinction between idealisations that represent reversible, solely (...) quantitative simplifications and those that represent irreversible, degenerate idealisations which collapse out essential theoretical structure. I argue that Cherniak's position is best understood as assigning the latter status to traditional rationality theories and that, so understood, his arguments may be illuminated, expanded, and certain common criticisms of them rebutted. The result, however, is a departure from traditional, formalist theories of rationality of a more radical kind than Cherniak contemplates, with widespread ramifications for philosophical theory, especially philosophy of science itself. (shrink)

D. H. Sharp has recently argued that Einstein, Podolsky, and Rosen failed to make good their claim that elementary quantum theory provides only an incomplete description of physical reality. Sharp expounds in detail three criticisms (a fourth is mentioned) which focus largely on formal features of the quantum theory. I argue, on grounds centered largely in our search for an adequate physical understanding of the micro domain, that each of these criticisms must be rejected. The original criticism of quantum theory (...) reemerges as a still-important baseline in our search for an adequate understanding of quantum theory. (shrink)

In this volume C.A. (Chet) Bowers, whose pioneering work on education and environmental and sustainability issues is widely recognized and respected around the world, brings together a carefully curated selection of his seminal work on the ideological, cultural, and linguistic roots of the ecological crisis; misconceptions underlying modern consciousness; the cultural commons; a critique of technology; and educational reforms to address these pressing concerns. In the World Library of Educationalists, international scholars themselves compile career-long collections of what they judge to (...) be their finest pieces - extracts from books, key articles, salient research findings, major theoretical and/practical contributions - so the world can read them in a single manageable volume. Readers will be able to follow the themes and strands of their work and see their contribution to the development of a field, as well as the development of the field itself. Contributors to the series include : Michael Apple, James A. Banks, Joel Spring, William F. Pinar, Stephen J. Ball, Elliot Eisner, Howard Gardner, John Gilbert, Ivor F. Goodson, Peter Jarvis. (shrink)

The National Gallery, London. 3 October 2020–24 January 2021.

Chad A Witt, Ramsey R Hachem Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, Saint Louis, MO, USA: The role of donor-specific antibodies to human leukocyte antigens and the burden of antibody-mediated rejection in lung transplantation remain enigmatic. Over the past several years, evidence has been emerging that humoral immunity plays an important role in the development of both acute and chronic lung allograft dysfunction. Multiple case reports and case series have identified (...) lung allograft recipients with clinical findings consistent with acute AMR. However, there is currently no widely accepted definition for AMR in lung transplantation, and this has been a significant barrier to furthering our understanding of this form of rejection. Nonetheless, the development of DSA after transplantation has consistently been identified as an independent risk factor for persistent and high-grade acute cellular rejection and CLAD. This has raised the possibility that chronic AMR may be a distinct phenotype of CLAD although evidence supporting this paradigm is still lacking. Additionally, antibodies to lung-restricted self-antigens have been associated with primary graft dysfunction early and the development of CLAD late after transplantation, and emerging evidence underscores significant interactions between autoimmunity and alloimmunity after transplantation. There is currently an active International Society for Heart and Lung Transplantation working group that is developing an operational definition for AMR in lung transplantation. This will be critical to improve our understanding of this form of rejection and conduct clinical trials to identify optimal treatment strategies. This review will summarize the literature on DSA and AMR in lung transplantation and discuss the impact of antibodies to self-antigens on lung allograft dysfunction. Keywords: antibody-mediated rejection, donor-specific antibodies, lung transplantation. (shrink)

Our trust in the word of others is often dismissed as unworthy, because the illusory ideal of "autonomous knowledge" has prevailed in the debate about the nature of knowledge. Yet we are profoundly dependent on others for a vast amount of what any of us claim to know. Coady explores the nature of testimony in order to show how it might be justified as a source of knowledge, and uses the insights that he has developed to challenge certain widespread assumptions (...) in the areas of history, law, mathematics, and psychology. (shrink)

This book seeks to examine the mutual interplay between existentialism and Christian belief as seen through the work of three existentialist thinkers who were also committed Christians - a Spaniard, a Russian, and a Frenchman. They are compared with each other and with leading non-religious existentialists. The major themes studied include reason, freedom, the self, belief, hope, love, suffering, and immortality.

Open peer commentary on the target article “From Objects to Processes: A Proposal to Rewrite Radical Constructivism” by Siegfried J. Schmidt. Upshot: Siegfried J. Schmidt’s process-oriented constructivism, with which he proposes to dissolve the debate about realism, offers myriad intellectual challenges to constructivists from numerous different disciplines. While “From Objects to Processes” seems to represent a review of Schmidt’s work rather than a new addition to the debate, it derives in a convincing fashion the importance of a process- and action-based (...) unending constructivism from a combination of Schmidt’s own previous positions and a number of central epistemological questions. (shrink)

(Statement of Responsibility) by C.A. Stephens ; illustrated.

It is a theorem of Prikry [7] that ifκcarries a uniformη-descendingly complete ultrafilter then the stationary reflection propertyfails. In this paper we will derive similar results, but here from properties of filters rather than ultrafilters.Throughoutκandηwill denote regular cardinals withη<κ, andIwill denote an ideal onκ, by which we mean a setI⊆P such that Iis closed under taking subsets and finite unions and αЄIfor eachα<κ, butκ∉I.Iis said to beμ-complete if it is closed under taking unions of size <μ,I* = {X⊆κ∣κ−XЄI} is the (...) filter dual toIand ifAЄI+ −I), thenI∣Ais the ideal onκgiven byI∣A= {X⊆κ∣X∩AЄI}. Ifh: A→κthenhis said to be unbounded modIif for eachα<κ,h−1 = {ξЄA∣h<α} ЄIand a least function forIifhis unbounded modIand wheneverg: A→κis a function, unbounded modI, then {ξЄA∣g{ξ) shrink)

C. A. J. Coady; VIII*—Descartes' Other Myth, Proceedings of the Aristotelian Society, Volume 83, Issue 1, 1 June 1983, Pages 121–142, https://doi.org/10.1093/ar.